Endocrine Abstracts

Objective: To investigate whether a supervised structured exercise program by 16 weeks improves metabolic, pulmonary and cardiovascular parameters in obese adolescents.Material and methods: We included 38 obese adolescents between 12–15 years old. They participated in a supervised exercise program by 90 minutes, 5 days a week during 16 weeks. At baseline and at the end of the exercise program, we evaluated cardiorespiratory fitness, anthropometric m...

Background: The fetal insulin hypothesis proposes that low birth weight, insulin resistance, and decreased insulin secretion in adulthood are genetically mediated. Babies with low birth weight have higher morbidity and mortality risk in adulthood. However, this situation could also occur in children with adequate weight at birth with genetic risk factors. The polymorphisms rs11708067 in ADCY5 and rs7754840 in CDKAL1 have been associated with low birth weight,...